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What are CAR-NK cells?

2022-01-10


Naturally occurring killer (NK) cells are genetically engineered to express specific chimeric antigen receptors (CARs), thereby enhancing their ability to target and kill tumor cells. CAR-NK cells combine the natural immune properties of NK cells with the precise targeting of CAR technology and are considered a significant breakthrough in tumor immunotherapy following CAR-T cell therapy.
What are CAR-NK cells?

CAR-NK cells (chimeric antigen receptor natural killer cells) are natural killer (NK) cells that have been genetically engineered to express a specific chimeric antigen receptor (CAR), thereby enhancing their ability to target and kill tumor cells. CAR-NK cells combine the innate immune properties of NK cells with the precise targeting of CAR technology and are considered a significant breakthrough in the field of tumor immunotherapy, following CAR-T cell therapy.


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What are NK cells?

An important component of the human immune system, belonging to the lymphocytes of innate (non-specific) immunity. It can quickly identify and kill abnormal cells (such as virus-infected cells or tumor cells) without prior contact with antigens.